Dynamic Axial Compression LC Columns
Simplified packing with best-in-class chromatographic performance.
DAC MPLC Columns
Many mid-sized therapeutics in the 4 to 15 kDa range, such as microbial- derived proteins and oligonucleotides, are purified using 15 to 40 μm chromatography media. Such processes generate higher backpressures than can be accommodated by a typical 6 or 10 bar column but don’t require the pressure rating and upfront capital cost of traditional preparative HPLC. For over a decade, Asahi Kasei Bioprocess has been a leader in 20 bar DAC MPLC Columns for these applications.
Check out our NEW DAC Ergo feature, built for DAC LC Columns
View DAC ErgoPack Your Column in Minutes
Transfer slurry into the column and reproducibly piston-pack your chromatography media in minutes. When it is time to unpack your column, use the same piston to easily push the media out of the column.
Active Flow Distribution
CAD-modeled “active” flow distribution generates uniform dispersal of your product and eluents across the entire column surface, even for columns packed with short bed heights, resulting in maximum chromatographic resolving power.
Greater Flexibility
Our DAC MPLC Columns are available with fully separated hydraulics. Columns with similar pressure ratings and internal diameters can be operated with a single hydraulic cart when the columns are not in use simultaneously. This unique feature reduces capital costs and maximizes resource allocation.
Comply With Industry Standards
Each column features 316L stainless steel construction with highly fluorinated, FDA-compliant seals that are compatible with typical organic and aqueous mobile phases. Full material traceability is provided for all stainless steel product contact parts.
Enjoy the Freedom of Customization
Several options are available so that you can customize your column to your particular application needs:
Features include:
- Electropolishing
- Jacketing and/or insulation for temperature control
- ASME code stamp
- CE Pressure Equipment Directive compliance
- IQ/OQ qualification package
Hundreds of chromatography columns installed worldwide
Product Options
DAC MPLC Columns
| Catalog No. | Column Dimensions | Pressure Rating |
| MP15x50 | 15 cm i.d. x 50 cm L | 20 bar |
| MP15x70 | 15 cm i.d. x 70 cm L | 20 bar |
| MP17x50 | 17 cm i.d. x 50 cm L | 20 bar |
| MP17x70 | 17 cm i.d. x 70 cm L | 20 bar |
| MP20x50 | 20 cm i.d. x 50 cm L | 20 bar |
| MP20x70 | 20 cm i.d. x 70 cm L | 20 bar |
| MP30x50 | 30 cm i.d. x 50 cm L | 20 bar |
| MP30x70 | 30 cm i.d. x 70 cm L | 20 bar |
| MP40x50 | 40 cm i.d. x 50 cm L | 20 bar |
| MP40x70 | 40 cm i.d. x 70 cm L | 20 bar |
| MP45x50 | 45 cm i.d. x 50 cm L | 20 bar |
| MP45x70 | 45 cm i.d. x 70 cm L | 20 bar |
| MP50x50 | 50 cm i.d. x 50 cm L | 20 bar |
| MP50x70 | 50 cm i.d. x 70 cm L | 20 bar |
| MP60x50 | 60cm i.d. x 50 cm L | 20 bar |
| MP60x70 | 60 cm i.d. x 70 cm L | 20 bar |
| MP80x50 | 80 cm i.d. x 50 cm L | 20 bar |
| MP80x70 | 80 cm i.d. x 70 cm L | 20 bar |
| MP100x50 | 100 cm i.d. x 50 cm L | 20 bar |
| MP100x70 | 100 cm i.d. x 70 cm L | 20 bar |
| MP120x50 | 120 cm i.d. x 50 cm L | 20 bar |
| MP120x70 | 120 cm i.d. x 70 cm L | 20 bar |
DAC MPLC Columns Hydraulic Carts
| Catalog No. | Description | Pressure Rating |
| MP-Cart-17 | Benchtop hydraulic cart for 15 -17 cm i.d. DAC MPLC columns | 20 bar |
| MP-Cart-30 | Hydraulic cart for 20-30 cm i.d. DAC MPLC column | 20 bar |
| MP-Cart-60 | Hydraulic cart for 40-60 cm i.d. DAC MPLC column | 20 bar |
| MP-Cart-100 | Hydraulic cart for 80-100 cm i.d. DAC MPLC column | 20 bar |