Asahi Axial Compression
Synthesis Columns

Proven design for mid-scale and large-scale solid phase oligosynthesis.

Simplified synthesis column packing and unpacking

Active Flow Distribution

CAD-modeled “active” flow distribution generates uniform dispersal of amidites and reagents across the entire column surface, even for columns packed with short bed heights, resulting in maximum coupling efficiency.

AsahiKasei 045 part

A Range of Features and Options

The Asahi ACS Column includes a slurry inlet port to simplify the loading of your solid support. Its slurry outlet port can be used to unpack your solid support, and also to take samples of your support during the synthesis process after depressurizing the column.

Other options include:

  • Electropolishing
  • Heating jackets
  • IQ/OQ documentation and execution
  • ASME Code stamp
  • CE marking with compliance to Pressure Equipment Directive
Asahi Kasei 035

Product Options

Catalog No. Column Dimensions Pressure Rating Adjustable Bed Height Theoretical DNA Capacity* Theoretical RNA Capacity**
ACS10 10 cm i.d. x 30 cm L 10 bar 4 – 15 cm 8 – 30 mmol 4 – 18 mmol
ACS15 15 cm i.d. x 30 cm L 10 bar 4 – 15 cm 40 – 70 mmol 18 – 40 mmol
ACS20 20 cm i.d. x 30 cm L 10 bar 4 – 15 cm 70 – 130 mmol 40 – 75 mmol
ACS30 30 cm i.d. x 30 cm L 10 bar 4 – 15 cm 130 – 280 mmol 75 – 160 mmol
ACS35 35 cm i.d. x 30 cm L 10 bar 4 – 15 cm 200 – 380 mmol 100 – 230 mmol
ACS40 40 cm i.d. x 30 cm L 10 bar 4 – 15 cm 280 – 500 mmol 160- 300 mmol
ACS45 45 cm i.d. x 30 cm L 10 bar 4 – 15 cm 300 – 630 mmol 190 – 380 mmol
ACS50 50 cm i.d. x 30 cm L 10 bar 4 – 15 cm 500 – 750 mmol 300 – 470 mmol
ACS60 60 cm i.d. x 30 cm L 10 bar 4 – 15 cm 0.75 – 1 mol 460 – 670 mmol
ACS70 70 cm i.d. x 30 cm L 10 bar 4 – 15 cm 0.80 – 1.5 mol 500 – 920 mmol
ACS80 80 cm i.d. x 30 cm L 10 bar 4 – 15 cm 1 – 2 mol 0.67 – 1.2 mol
ACS100 100 cm i.d. x 30 cm L 10 bar 4 – 15 cm 2 – 3 mol 1.2 – 1.8 mol

Note: Customized Asahi SCS and Asahi ACS columns are available upon request.

* Based on 200 μmol/g loading for DNA synthesis and maximum bed height of 10 cm.
** Based on 120 μmol/g loading for RNA synthesis and maximum bed height of 10 cm.
Capacity is approximate and depends on your process, bed height and solid support loading.

NEW PRODUCT BROCHURE!

Planova Single-Use Virus Filtration Controller

Digital Download