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CURSIV™ Liquid Chromatography

DAC HPLC Column

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Product Overview

DAC HPLC Column

Smaller molecular weight therapeutics commonly require chromatography media with particle sizes of 10 to 15 μm for successful purification. Such media generate backpressures of 70 bar or higher. Asahi Kasei Bioprocess has been supplying DAC HPLC Columns for these applications for over two decades.
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Up to 100
Barg
10 to 15 µm
Spherical Silica Gels Compatible
Peptide
Purifications

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Benefits

Pack Your Column in Minutes

Transfer slurry into the column and reproducibly piston-pack your chromatography media in minutes. When it is time to unpack your column, use the same piston to easily push the media out of the column.

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Fully moveable piston to achieve precise bed height
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Since high pressure columns are commonly used during peptide purifications. 70 and 100 bar ranges are designed to be comparable with 10 to 15 μm spherical silica gels.

Active Flow Distribution

CAD-modeled “active” flow distribution generates uniform dispersal of your product and eluents across the entire column surface, even for columns packed with short bed heights, resulting in maximum chromatographic resolving power.

Greater Flexibility

Our DAC HPLC Columns are available with fully separated hydraulics. Columns with similar pressure ratings and internal diameters can be operated with a single hydraulic cart when the columns are not in use simultaneously. This unique feature reduces capital costs and maximizes resource allocation.

applications

Enjoy the Freedom of Customization

Several options are available so that you can customize your column to your particular application needs:

Features include:

  • Electropolishing
  • ASME code stamp
  • CE Pressure Equipment Directive compliance
  • IQ/OQ qualification package

Resources

DAC HPLC Column

Catalog No. Column Dimensions Pressure Rating
HP6x50 6 cm i.d. x 50 cm L 100 barg
HP6x70 6 cm i.d. x 70 cm L 100 barg
HP7.5×50 7.5 cm i.d. x 50 cm L 100 barg
HP7.5×70 7.5 cm i.d. x 70 cm L 100 barg
HP10x50 10 cm i.d. x 50 cm L 100 barg
HP10x70 10 cm i.d. x 70 cm L 100 barg
HP15x50 15 cm i.d. x 50 cm L 70 barg
HP15x70 15 cm i.d. x 70 cm L 70 barg
HP17x50 17 cm i.d. x 50 cm L 70 barg
HP17x70 17 cm i.d. x 70 cm L 70 barg
HP20x50 20 cm i.d. x 50 cm L 70 barg
HP20x70 20 cm i.d. x 70 cm L 70 barg
HP30x50 30 cm i.d. x 50 cm L 70 barg
HP30x70 30 cm i.d. x 70 cm L 70 barg
HP40x50 40 cm i.d. x 50 cm L 70 barg
HP40x70 40 cm i.d. x 70 cm L 70 barg
HP45x50 45 cm i.d. x 50 cm L 70 barg
HP45x70 45 cm i.d. x 70 cm L 70 barg
HP50x50 50 cm i.d. x 50 cm L 70 barg
HP50x70 50 cm i.d. x 70 cm L 70 barg
HP60x50 60 cm i.d. x 50 cm L 70 barg
HP60x70 60 cm i.d. x 70 cm L 70 barg
HP80x50 80 cm i.d. x 50 cm L 70 barg
HP80x70 80 cm i.d. x 70 cm L 70 barg
HP100x50 100 cm i.d. x 50 cm L 70 barg
HP100x70 100 cm i.d. x 70 cm L 70 barg

Publications and More

Diagrams available upon request.

What pressure ratings do these high-pressure columns support?

These columns are designed with pressure ratings of 70 and 100 bar, making them suitable for demanding purification processes.

What materials are used in the construction of the HPLC columns?

The HPLC columns feature 316L stainless steel construction, providing durability and resistance to corrosion.

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