Bioprocess Chrom Systems
Combining gradient and inline buffer dilution capability
with powerful software to your specifications.
Capture and polishing remain critical steps for achieving the product purity desired in today’s downstream processes for biopharmaceuticals and plasma derivatives. Our BPC System platform is available in capacities suitable for process development/scale-up, clinical manufacturing and commercial manufacturing, with pump turndowns up to 100X in either polymeric or stainless steel construction.
Classic BPC Systems
Utilize a BPC System in either gradient formation or inline buffer dilution mode for greater flexibility.
BPC Systems in Gradient Formation Mode (flow control or conductivity control)
BPC Systems in Inline Buffer Dilution Mode (flow control or conductivity control)
Next-Gen Bioprocess IBD-Chrom Systems
Our next-generation technology embodies our most powerful BPC System to date: combining inline buffer dilution and bioprocess chromatography. With a three-pump Bioprocess IBD-Chrom (BIC) System, a buffer concentrate and salt concentrate are diluted with WFI while simultaneously producing a linear salt gradient.
Freedom of Customization
Standard configuration BPC and BIC Systems suitable for typical applications are available with short lead times. However, your unique purification processes or multi-product applications may require a system that is different than the standard offerings.
Customizable options include:
- Number of inlet ports or fractions
- End-of-stream air sensors
- Sample injection loops
- Heat exchangers
- Software customization
- Hazardous area ratings (NFPA and ATEX)
- Modified footprints to fit into tight spaces and within fume hoods
Software Designed For You
Off-the-shelf chromatography systems may provide familiar software, but have rigid hardware constraints; conversely, systems with customized hardware are typically burdened with cumbersome and dated software. You no longer have to compromise.
Custom BPC Systems with flow rates up to 15,000 L/h are available
|4-150 L/h; polymeric
|4-150 L/h; stainless steel
|6 – 300 L/h; polymeric
|6 – 300 L/h; stainless steel
|50 – 900 L/h; polymeric
|50-900 L/h; stainless steel
|100-1800 L/h; polymeric
|100 – 1800 L/h; stainless steel
|180 L/h stainless steel
|600 L/h stainless steel
|1200 L/h stainless steel
|1800 L/h stainless steel