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CURSIV® Liquid Chromatography

DAC UHPLC Column

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Product Overview

DAC UHPLC Column

Certain difficult-to-purify peptides require the use of require chromatography media with particle sizes 5 μm at preparative scale to achieve the necessary product purity. Asahi Kasei Bioprocess has innovated DAC UHPLC Columns with pressure rating of 200 bar for these demanding applications.
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≤ 200 Barg
Pressure Rating
≥5 µm
Silica Gels Compatible
Ideal
For Clean Rooms

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Benefits

Pack Your Column in Minutes

Ideal for challenging peptide purifications. Transfer slurry into the column and reproducibly piston-pack your chromatography media in minutes. When it is time to unpack your column, use the same piston to easily push the media out of the column.

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Fully moveable piston to achieve precise bed height 
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When greater resolution is required, our ultra-high performance liquid chromatography (UHPLC) columns tolerate pressures of up to 200 bar, enabling the use of silica gels as small as 5 μm. UHPLC columns are especially attractive for challenging peptide purifications.

Active Flow Distribution

CAD-modeled “active” flow distribution generates uniform dispersal of your product and eluents across the entire column surface, even for columns packed with short bed heights, resulting in maximum chromatographic resolving power.

Greater Flexibility

Our DAC UHPLC Columns are available with fully separated hydraulics. Columns with similar pressure ratings and internal diameters can be operated with a single hydraulic cart when the columns are not in use simultaneously. This unique feature reduces capital costs and maximizes resource allocation.

applications

Enjoy the Freedom of Customization

CURSIV DAC UHPLC FrontView

Several options are available so that you can customize your column to your particular application needs:

Features include:

  • Electropolishing
  • ASME code stamp
  • CE Pressure Equipment Directive compliance
  • IQ/OQ qualification package

Resources

DAC UHPLC Column

Catalog No. Column Dimensions Pressure Rating
DAC-6-50-200 6 cm ID x 50 cm L 200 barg
DAC-7.5-50-200 7.5 cm ID x 50 cm L 200 barg
DAC-10-50-200 10 cm ID x 50 cm L 200 barg
DAC-15-50-200 15 cm ID x 50 cm L 200 barg
DAC-17-50-200 17 cm ID x 50 cm L 200 barg
DAC-20-50-200 20 cm ID x 50 cm L 200 barg
DAC-30-50-200 30 cm ID x 50 cm L 200 barg
DAC-40-50-200 40 cm ID x 50 cm L 200 barg
DAC-45-50-200 45 cm ID x 50 cm L 200 barg
DAC-50-50-200 50 cm ID x 50 cm L 200 barg
DAC-60-50-200 60 cm ID x 50 cm L 200 barg

Publications and More

CURSIV® Liquid Chromatography Columns Brochure

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Diagrams available upon request.

Why are UHPLC columns particularly useful for peptide purification?

UHPLC columns are ideal for peptide purifications that require high resolution and performance. The ability to handle high pressures and use small silica gels makes them well-suited for the precise and efficient separation of complex peptide mixtures.

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