THESYS™ OLIGONUCLEOTIDE SYNTHESIS

ACS ERGO Column

Product Overview

ACS ERGO Column

ACS ERGO provides the same reliable high performance you are used to from our other synthesis columns but is uniquely engineered to simplify the time between batches. No longer does performing routine maintenance need to be such a time-intensive process with several complicated steps to disassemble, empty, clean and reassemble just as the next batch is ready to be run.

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Benefits

Ergonomic Innovation

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Bolt-Free Design: Simplifies disassembly, cleaning, and reassembly, reducing downtime between batches.
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Dynamic Piston Movement: Allows for easy and precise setting of the fixed bed height, enhancing efficiency during setup.

Key Features

  • Bolt free design (innovative I-bar format) to improve efficiency of removing the top of the column to access the process chamber.
  • Unique frame with ergonomic handle assembly to facilitate smooth, safe unpacking and cleaning.
    • Capable of handling columns up to 85 cm i.d.
    • Capable of locking at 25-degree intervals with built-in safety mechanisms to prevent accidental rotation.
  • Dynamic piston movement, to allow for simpler bed height adjustment.
  • Minimized footprint to integrate into manufacturing floor seamlessly.
  • Safe, lockable casters.

Smooth Column Changeover in 9 Easy Steps

  1. Secure column in vertical position with upper section attached to overhead hoist.
  2. Remove I-bars and store in convenient storage location on column frame.
  3. Lift upper section with overhead hoist.
  4. Tilt column for discharging solid support and cleaning.
  5. Return column to vertical position and remove bottom plate.
  6. Change frits and seals on upper section and bottom plate.
  7. Replace bottom plate and charge new solid support into column.
  8. Replace upper section by lowering back into place and reinstall I-bars.
  9. Lower piston to achieve desired bed height and prepare for next batch.

Resources

ACS ERGO Column

Catalog No. Description Diameter Stroke Length (BH) Pressure
ACSE1-10-30-10 ACS Ergo Size 1 (F070 Gearbox) 10 cm 30 cm 10 barg
ACSE1-15-30-10 ACS Ergo Size 1 (F070 Gearbox) 15 cm 30 cm 10 barg
ACSE1-20-30-10 ACS Ergo Size 1 (F070 Gearbox) 20 cm 30 cm 10 barg
ACSE1-25-30-10 ACS Ergo Size 1 (F070 Gearbox) 25 cm 30 cm 10 barg
ACSE1-30-30-10 ACS Ergo Size 1 (F070 Gearbox) 30 cm 30 cm 10 barg
ACSE1-35-30-10 ACS Ergo Size 1 (F070 Gearbox) 35 cm 30 cm 10 barg
ACSE1-40-30-10 ACS Ergo Size 1 (F070 Gearbox) 40 cm 30 cm 10 barg
ACSE1-45-30-10 ACS Ergo Size 1 (F070 Gearbox) 45 cm 30 cm 10 barg
ACSE1-50-30-10 ACS Ergo Size 2 (F076 Gearbox) 50 cm 30 cm 10 barg
ACSE1-60-30-10 ACS Ergo Size 2 (F076 Gearbox) 60 cm 30 cm 10 barg

Publications and More

Diagrams available upon request.

How does the dynamic piston movement mechanism function, and what benefits does it offer in terms of operational efficiency and performance consistency?

The ACS column piston can be adjusted quickly using the hydraulic cart from a DAC LC column, allowing for rapid bed height changes. This method is faster and safer than the traditional TP bolt tightening, which risks tilting.

Are there any specific cleaning or maintenance protocols recommended for the ACS ERGO to ensure optimal performance and longevity of the equipment?

The cleaning and maintenance protocols for the ACS ERGO are the same as those recommended for DAC LC columns. These protocols are typically detailed in the user manual provided with the equipment.

What mechanisms are in place to ensure precise control over bed height adjustment, and how does this contribute to the reproducibility and quality of synthesized products?

The hydraulic controls allow ease of bed height adjustment.

How does the bolt-free design work and how does it contribute to the efficiency of maintenance procedures?

The ACS Ergo column body connects via I-bars that can be easily engaged or disengaged, speeding up assembly and disassembly compared to using bolts.

Can I use this column in a hazardous environment with the rest of my synthesis equipment?

Yes, the ACS Ergo is rated for use in a Zone I environment.

How do I lift the top plate off for cleaning and changeover? Will I require a hoist

Both the top half of the ACS Ergo column body and the top plate/piston assembly can be removed for maintenance, which requires a hoist with appropriate load capability and hazardous area rating as appropriate for the maintenance environment.

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